http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104447397-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C251-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C249-02 |
| filingDate | 2014-12-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-04-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-04-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104447397-B |
| titleOfInvention | The synthesis of 3,5-Dibromosalicylaldehyde contracting AMPD schiff bases with anticancer activity and application |
| abstract | The invention discloses a kind of synthetic method and application of 3,5-Dibromosalicylaldehyde contracting AMPD schiff bases with anticancer activity.The molecular formula of 3,5-Dibromosalicylaldehyde contracting AMPD schiff bases is: Cn 11 hn 13 brn 2 nOn 3 , molecular weight is: 366.93, has good antitumour activity.(1) by analytically pure for 2.799g 3,5-Dibromosalicylaldehyde is placed in there-necked flask, the dehydrated alcohol heated and stirred adding 15ml treats that it dissolves completely, then the analytically pure 2-amino-2-methyl-1 of 1.051g is added, ammediol, then the dehydrated alcohol adding 10ml, heating in water bath, design temperature is 65 DEG C, return stirring about 120 minutes.(2) cool under room temperature, naturally to volatilize crystallization, standing after 3 days, obtain yellow bulk crystals.3,5-Dibromosalicylaldehyde contracting AMPD schiff bases is applied to making cancer therapy drug.The present invention has that technique is simple, with low cost, chemical composition is easy to control, reproducible and output advantages of higher. |
| priorityDate | 2014-12-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 20.