http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104447375-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_49790ed5b8ddc5fa27a1d47732c612df |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C255-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D295-145 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C229-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C227-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C255-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-04 |
filingDate | 2014-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0340350101c82fc2e754aaa07aa5f79c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3d66d76b89393da41f579bd650f07da5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_923347978aa80323d93acb335b11c043 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_be815d2e1b7d99e043d75e2961887d08 |
publicationDate | 2015-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-104447375-A |
titleOfInvention | Chiral α-amino-δ-oxopentanoate derivatives and their synthesis methods and applications |
abstract | The invention discloses a method for synthesizing optically pure α-amino-δ-oxopentanoic acid ester derivatives, which uses diazo compounds, imines and enamines as raw materials, and uses allyl palladium chloride and chiral phosphoric acid as raw materials. Catalyst, with organic solvent as solvent, The molecular sieve is a water absorbing agent, and the optically active α-amino-δ-oxopentanoate derivative is obtained through one-step reaction at -20-0°C. The synthesis method of the optically active α-amino-δ-oxopentanoate derivatives of the present invention has the advantages of efficient atom economy, high selectivity, low catalyst consumption, simple and safe operation, etc. The synthesized α-amino-δ- Oxyvalerate derivatives are important organic synthesis and pharmaceutical intermediates. |
priorityDate | 2014-11-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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