| Predicate |
Object |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate |
2013-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2017-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate |
2017-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-104436189-B |
| titleOfInvention |
Key protein Numb for cholesterol absorption in liver and intestine and application thereof |
| abstract |
The invention discloses a key protein Numb for cholesterol absorption in liver and intestine and an application thereof. Particularly, disclosed are an application of a Numb protein inhibitor in regulating cholesterol absorption and an application of an inhibitor with combined Numb protein with NPC1L1 protein. The invention further discloses a NPC1L1 mutant protein which can't be combined with Numb, and thus the cholesterol absorption mediated by the NPC1L2 protein can be reduced. |
| priorityDate |
2013-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |