http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104418928-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H1-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-167 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-167 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H1-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H1-00 |
| filingDate | 2013-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2017-03-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104418928-B |
| titleOfInvention | A kind of preparation method of 1,4-butanedisulfonic acid adenosylmethionine |
| abstract | The invention discloses a preparation method of 1,4-butanedisulfonic acid adenosylmethionine: acidifying the fermentation broth of adenosylmethionine-producing bacteria, filtering to obtain wet bacteria, drying, freeze-thawing, and mixing the aqueous solution of inorganic strong acid and wet Mix the bacteria evenly; filter the acid solution containing the broken bacteria in a ceramic membrane, add an aqueous solution of a strong inorganic acid, and collect the filtrate; filter the filtrate through a nanofiltration membrane to obtain a concentrated solution A; pass through a medium-polarity macroporous adsorption resin Column, after washing with water, the effluent B is obtained; the H + type macroporous weakly acidic cation exchange resin column is passed through, and the H + type macroporous acidic cation exchange resin column is eluted with 1,4-butanedisulfonic acid, and the effluent is distributed and collected. C is combined; the collected solution is passed through ultrafiltration membrane and nanofiltration membrane in turn; the concentrated solution D is mixed with 1,4-butanedisulfonic acid, the ratio of 1,4-butanedisulfonic acid and adenosylmethionine is adjusted, and it is obtained after drying . The preparation method of the invention is simple in operation, high in product yield, white in color and high in purity. |
| priorityDate | 2013-08-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 48.