http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104402984-B
Outgoing Links
Predicate | Object |
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classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-47 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-30 |
filingDate | 2014-11-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2018-09-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2018-09-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-104402984-B |
titleOfInvention | A kind of preparation method of the iron protein succinylate of high amount of iron load |
abstract | The invention belongs to pharmaceutical technology fields, are related to a kind of preparation method of high amount of iron load iron protein succinylate.It is acylated:Succinic anhydride reaction is added into casein solution, reacting liquid pH value 6 ~ 9 is kept by being continuously added sodium hydroxide solution, after having reacted, acid adding makes reacting liquid pH value 1 ~ 4, filters to obtain precipitation;Carry iron:Obtained precipitation is dispersed in water, appropriate sodium hydroxide solution is added to be stirred to dissolve, the liquor ferri trichloridi containing sodium bicarbonate is added dropwise into dissolving gained succinic acid protein solution, the pH value 6 ~ 9 that sodium hydroxide solution maintains reaction solution is added dropwise simultaneously, filtering after having reacted removes insoluble matter and obtains iron protein succinylate solution;Refined to remove insoluble matter, then acid adding precipitates, and filters out precipitation, dry after washing.The amount of iron load of the iron protein succinylate of document report is 4.5% ~ 10% at present.Iron protein succinylate iron content prepared by the method for the present invention is up to 15%, and simple for process, and product dissolubility is good, stable quality. |
priorityDate | 2014-11-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 113.