http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104402868-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-05 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B59-002 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-14 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-14 |
| filingDate | 2014-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104402868-B |
| titleOfInvention | Deuterated Crizotinib crystal formation and preparation method thereof |
| abstract | The invention discloses a kind of deuterated Crizotinib crystal formation and preparation method thereof, described crystal formation includes the deuterated Crizotinib crystal formation as shown in structure formula (I) or structure formula (II), and gives this diffraction maximum that two kinds of crystal formations represent in X ray powder diffraction pattern with 2 θ angles.The preparation method of the deuterated Crizotinib crystal formation of the present invention, it is that deuterated Crizotinib is dissolved in organic solvent, by adding water and staged cooling after intensification, it is achieved that the preparation of the crystal formation of the deuterated Crizotinib as shown in structure formula (I) or structure formula (II)；This preparation method gained crystal formation has higher structural homogeneity and crystal form purity, and yield is high；This preparation method technique is simple, easy to operate, low cost, it is easy to Automated condtrol, is suitable for popularization and application. |
| priorityDate | 2014-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 34.