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filingDate 2014-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2016-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2016-11-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-104387344-B
titleOfInvention A kind of macrocyclic diterpene compounds separating from the thick root root of Beijing euphorbia and purposes
abstract The present invention relates to a kind of from the thick root root of Beijing euphorbia separate macrocyclic diterpene compounds and purposes, described from the thick root root of Beijing euphorbia ( Euphorbia macrorrhiza C. A. Mey) in separate macrocyclic diterpene compounds be belonging respectively to 5 kinds of different diterpene framework types, the present invention described macrocyclic diterpene compounds has been carried out in vitro cytotoxic effect measure and anti-drug-resistance activity measure.Test result indicate that, the macrocyclic diterpene compounds separating from the thick root root of Beijing euphorbia has cytotoxic activity in various degree to human mouth epidermoid carcinoma KB cell and human mouth epidermoid carcinoma persister KBv200, and there is certain anti-drug-resistance activity, can be used for preparing antineoplastic.
priorityDate 2014-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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