http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104379598-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-31 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-61 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-8125 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K1-16 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-61 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-16 |
| filingDate | 2013-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-04-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2017-04-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104379598-B |
| titleOfInvention | Long-acting human growth hormone's albumen of high glycosylation and its production method |
| abstract | The present invention relates to a kind of high glycosylation long-acting human growth hormone NexP hGH albumen highly long-acting in vivo, and it is related to its preparation method.More particularly it relates to the concrete isotype of long-acting human growth hormone NexP hGH albumen, wherein human growth hormone are merged with the alpha1 Anti-trypsin mutant of high glycosylation, so as to increase internal long-acting performance, and it is related to its production method.Considering that, the present invention also relates to be used for the high-purity purification process of NexP hGH, the method is specifically comprised the steps of in the range of persistence human growth hormone's production method：A () is to carrying out anion exchange resin chromatograph with the biological emulsion of the long-acting human growth hormone NexP hGH of alpha1 Anti-trypsin mutant fusion comprising wherein human growth hormone；B () carries out hydrophobic resin chromatograph to the eluate produced in the biological emulsion comprising NexP hGH or step (a)；(c) eluate to producing in the biological emulsion comprising long-acting human growth hormone NexP hGH and step (a) or step (b) carries out affinity chromatography, and the affinity chromatography has loaded the resin of the anti-alpha1 Anti-trypsin antibody fragment of attachment. |
| priorityDate | 2012-06-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 204.