| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b3b518e0b6562f18cd81e63ccafc7d4d |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12R2001-645 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-145
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P13-002 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-645 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P13-00 |
| filingDate |
2014-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2b51e663026059574550a2327747c8c6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cffff5d04a14dfa11f21a0b45f9285a9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7aa8d34e78467901567bc90d10efbdb7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_44be30c1eab1fe30f4a17230e25006ab
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_60956fcc76f33750c2f837af6f084e9d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_64fd0276b1847ee6a37edb6956c462da
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_03fa8e6263dfa5619691abddd491ec73
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_edb3d47ed0461d8c0c65b68b63661bad
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_acbd9ba0a779e1d4ee1f25a88f65da41 |
| publicationDate |
2015-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-104371935-A |
| titleOfInvention |
Candida boidinii and application thereof |
| abstract |
The invention provides a Candida boidinii, of which the collection number is CGMCC 9446 and the complete name is Candida boidinii T1. The invention also provides application of the Candida boidinii T1 in catalytic synthesis of an atorvastatin intermediate, which is specifically implemented by catalytic synthesizing tert-butyl 6-cyano-(3R,5R)-dihydroxyhexanoate from the substrate tert-butyl 6-cyano-(5R)-hydroxy-3-carbonylhexanoate. The Candida boidinii can express high-stereoselectivity carbonyl reductase; and the conversion rate of the tert-butyl 6-cyano-(5R)-hydroxy-3-carbonylhexanoate is up to 99%, and the d.e. value of the product tert-butyl 6-cyano-(3R,5R)-dihydroxyhexanoate is up to 100%. |
| priorityDate |
2014-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |