http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104370851-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c3266bfb817389743f60ea262679e2be |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-28 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-28 |
| filingDate | 2013-08-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_21e422d0cb459307783a194c7d699fb8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5ed9059edfed39cc6a93482684c76f1c |
| publicationDate | 2015-02-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104370851-A |
| titleOfInvention | A kind of synthetic method of 2-aminomethyl-thiazole hydrochloride |
| abstract | The invention discloses a method for synthesizing 2-aminomethyl-thiazole hydrochloride. Boc-glycine ethyl ester is used as a starting material, and Boc-glycine amide is first ammoniated to obtain Boc-glycine amide, and then reacted with Lawesson reagent in tetrahydrofuran solution to obtain Boc-aminoethanethionamide, followed by a ring-closing reaction with bromoacetaldehyde to obtain the key intermediate 2-N-Boc-aminomethyl-thiazole, and finally remove Boc in hydrochloric acid-methanol solution to obtain the target product 2-aminomethyl Base-thiazole hydrochloride. The method has mild and simple reaction conditions, low cost, high yield, easy operation and is suitable for industrial production. |
| priorityDate | 2013-08-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 15.