http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104356206-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-04 |
filingDate | 2011-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2017-07-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2017-07-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-104356206-B |
titleOfInvention | HRP5 analogue and preparation method thereof |
abstract | The invention belongs to the field of medicine, and in particular relates to HRP5 analogs and a preparation method thereof. The general formula of the amino acid sequence of the HRP5 analog involved in the present invention is shown in SEQ ID NO: 2: Xaa1-Xaa2-Xaa3-Xaa4-Xaa5-Xaa6-Xaa7-Xaa8-Xaa9-Leu-Xaa11-Lys-Tyr-Leu-Leu Arg‑Xaa16‑Xaa17‑Xaa18. In vitro activity assays show that the polypeptide provided by the invention has significant bactericidal effect on Gram-positive bacteria, Gram-negative bacteria and fungi, and has a significant bactericidal effect on clinically isolated drug-resistant Gram-positive bacteria, drug-resistant Gram Negative bacteria and drug-resistant fungi also have significant bactericidal effects, with broad-spectrum and high-efficiency characteristics. |
priorityDate | 2011-05-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 81.