http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104356197-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K7-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-06 |
| filingDate | 2014-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2018-01-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104356197-B |
| titleOfInvention | A kind of Carfilzomib intermediate and preparation method thereof, and a kind of preparation method of Carfilzomib |
| abstract | The invention provides a kind of Carfilzomib intermediate, has structure shown in formula (XIII)；The preparation process of the intermediate is simple, only relates to condensation between amino acid, deprotection reaction, and reaction condition is gently controllable.Carfilzomib is prepared as raw material using the intermediate, only carry out epoxidation reaction, and the epoxidation reaction condition used has higher selectivity, improve the yield and purity of Carfilzomib, the Carfilzomib yield of preparation is more than 35%, purity is more than 99%, and an economy, environmentally friendly synthesis technique are provided for the preparation of Carfilzomib. |
| priorityDate | 2014-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 137.