| abstract |
The invention provides a kind of such as following formula（I）Two aryl amide derivatives of shown structure or its pharmaceutically acceptable salt, its preparation method, composition and its medical usage comprising it.Formula of the present invention（I）Two aryl amide derivatives of shown structure or its pharmaceutically acceptable salt have antagonism to FXR, and whole animal experiment shows, the effect of such compound has hypoglycemic, reducing blood lipid.Such compound can be used for treatment high fat of blood and diabetes B. |