abstract |
Disclosed herein are derivatizations of purines, 3H-imidazo[4,5-b]pyrimidines and 1H-imidazo[4,5-d]pyrazines of formula I that inhibit the activity of diacylglycerol acyltransferase 2 (DGAT2) and their use in treating diseases associated with the activity of DGAT2 in animals. |