| abstract |
The invention discloses an R-type aminotransferase and application thereof. The R-type omega-aminotransferase contains the amino acid sequence disclosed as SEQ ID NO:2, or the omega-aminotransferase-active protein amino acid sequence with high stereoselectivity-R configuration catalytic activity, which has at least 80% of homogeneity with the amino acid sequence disclosed as SEQ ID NO:2 or is subjected to substitution, deficiency or addition of one or more amino acids, wherein the high stereoselectivity means that the content of one stereomer is at least 1.1 times or so of the other stereomer. The R-type omega-aminotransferase has high stereoselectivity, can efficiently synthesize R configuration chiral amines with higher chiral purity, and is suitable for industrial production of chiral amines. |