http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104326965-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D209-42 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4045 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-405 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D209-14 |
filingDate | 2014-10-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2017-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2017-01-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-104326965-B |
titleOfInvention | Indole-containing amine compounds, and preparation method and application thereof |
abstract | The invention discloses indole amine compounds and pharmaceutically acceptable salts thereof. The compounds have favorable activities for inhibiting tumors from generation and transfer, have obvious inhibiting actions on mammary cancer cells, are excellent antitumor lead compounds, can be further developed into antineoplastic drugs for tumor metastasis, advanced tumors, nonsolid tumors and other cancers, and has potential and wide application prospects in the field of tumor therapy. The compounds are prepared by carrying out amine alkylation reaction on the halogenation part and primary amine part in a DMSO (dimethyl sulfoxide) solvent; and the method is simple and suitable for industrial production. |
priorityDate | 2014-10-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 33.