http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104326959-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D205-08 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D205-08 |
filingDate | 2014-11-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2016-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2016-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-104326959-B |
titleOfInvention | A kind of preparation method of Ezetimibe isomers |
abstract | The invention belongs to pharmaceutical chemistry field, the invention discloses a kind of Ezetimibe isomers (SSR type isomers), be 1-(4-fluorophenyl)-3 (S)-[3-(4-fluorophenyl)-3 (S)-hydroxypropyls]-4 (R)-(4-hydroxyphenyl)-2-azetidine (azetidine) ketone, and preparation method thereof. SSR type isomers is one of major impurity of Ezetimibe bulk drug. Synthetic by Ezetimibe SSR type isomers, for Ezetimibe determination of foreign matter, quantitatively and qualitative analysis reference substance is provided, thereby improved the quality standard of Ezetimibe. |
priorityDate | 2014-11-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 33.