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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D205-08
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D205-08
filingDate 2014-11-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2016-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2016-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-104326959-B
titleOfInvention A kind of preparation method of Ezetimibe isomers
abstract The invention belongs to pharmaceutical chemistry field, the invention discloses a kind of Ezetimibe isomers (SSR type isomers), be 1-(4-fluorophenyl)-3 (S)-[3-(4-fluorophenyl)-3 (S)-hydroxypropyls]-4 (R)-(4-hydroxyphenyl)-2-azetidine (azetidine) ketone, and preparation method thereof. SSR type isomers is one of major impurity of Ezetimibe bulk drug. Synthetic by Ezetimibe SSR type isomers, for Ezetimibe determination of foreign matter, quantitatively and qualitative analysis reference substance is provided, thereby improved the quality standard of Ezetimibe.
priorityDate 2014-11-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 33.