http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104324013-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-404 |
| filingDate | 2014-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-09-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2017-09-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104324013-B |
| titleOfInvention | The preparation technology of indapamide slow release agent |
| abstract | The present invention relates to the preparation method of indapamide slow release medicine, it is therefore an objective to so that the indapamide medicine prepared has better performance.The step of preparation technology, includes：A. get the raw materials ready in proportion：Indapamide 0.5% 2%, framework material：30% 50%, lactose 20% 35%, the PVP K30 of the lactose of 100 mesh 14% 28%, 200 mesh：10 20%, lubricant 0.2% 2%；B. indapamide bulk drug is mixed with the lactose of two kinds of fineness according to gradient incremental method；C. it is well mixed again with framework material, PVP K30；D. lubricant is added again, be well mixed；E. tabletting is produced.The present invention uses technique of direct powder compression, it the advantage is that main ingredient is more evenly distributed in tablets, the uniformity of tablet is more preferably (small content tablet need to control uniformity index), the influence of water, heat drying that conventional fabrication processes are brought to main ingredient quality can be avoided again in the fabrication process simultaneously, energy consumption is reduced, production efficiency is improved. |
| priorityDate | 2014-10-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 32.