http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104307002-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K101-02 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K51-04 |
| filingDate | 2014-09-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-08-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2017-08-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104307002-B |
| titleOfInvention | A kind of carrier-free of suitable clinical practice [*I] MIBG preparation method and application |
| abstract | The invention provides a kind of carrier-free of suitable clinical practice [ * I] MIBG preparation method, be freeze-dried to obtain freeze-dried powder by the way that tributyltin base benzyl guanidine to be dissolved in alcohols solvent and be added in appropriate phosphate buffer, then the powder after freezing be added to and contained * In the aqueous solution of I ions, it is subsequently added in oxidant and acidic buffer and reacts, because the freeze-dried powder of tributyltin base benzyl guanidine is water insoluble, therefore after completion of the reaction, can easily remove unreacted tributyltin base benzyl guanidine in reaction solution, obtain [ * I] MIBG not only high incomes, mark rate is high, and the accessory substance of the tin after unreacted tin precursor and reaction can be removed easily completely, free from foreign meter so that the carrier-free of preparation [ * I] MIBG can be more suitable for clinical practice with direct injection in human body. |
| priorityDate | 2014-09-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 45.