http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104293834-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-26 |
| filingDate | 2014-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2018-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2018-03-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104293834-B |
| titleOfInvention | GLP 1 or its analog and antibody Fc fragment fusion protein preparation method |
| abstract | The present invention relates to biological technical field, more particularly to a kind of GLP 1 or its analog and antibody Fc fragment fusion protein preparation method.The present invention provides the preparation method of a kind of GLP 1 or its analog and antibody Fc fragment fusion protein, comprises the following steps：GLP 1 or its analog are cloned into expression vector with antibody Fc fragment fusion protein coded sequence；Expression vector is transfected into CHO DXB11 cells, cultivates and filters out positive cell strain；Gained cell is expressed, after purification, produces the fusion protein.Preparation method provided by the present invention expresses the Fc molecules of GLP 1 in Chinese hamster ovary celI system DXB11, will not produce degradation problem, and follow-up purification yield greatly improves, and biological activity does not weaken, and is especially suitable for technique industry production requirement. |
| priorityDate | 2014-10-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 240.