http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104292280-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H1-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 |
| filingDate | 2014-10-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104292280-B |
| titleOfInvention | A kind of ammonia sugar thiazole derivative and synthetic method thereof and purposes |
| abstract | The invention discloses a kind of ammonia sugar thiazole derivative and synthetic method thereof.Be raw material with glucosamine hydrochloride during synthesis, benzylic ether protection is carried out to hydroxyl, achieve amino selective reaction, synthesize new intermediate glycosyl thiourea-N-(1, 3, 4, 6-tetra--O-benzyl-2-deoxidation-<i> β </i>-D-Glucopyranose-2-base) thiocarbamide, itself and the bromo-2-of 1-replace ethyl ketone cyclization, synthesize glycosyl thiazole-N-(1, 3, 4, 6-tetra--O-benzyl-<i> β </i>-D-Glucopyranose-2-base)-2-amino-4-substituted thiazole.The present invention is simple to operate safe, applied widely, cheaper starting materials is easy to get, aftertreatment is easy, yield is high, it is a kind of synthetic method rapidly and efficiently, the compound simultaneously synthesized has strong restraining effect to acetylcholinesterase, preparing in anti-acetylcholinesterasemedicine medicine, have broad application prospects. |
| priorityDate | 2014-10-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 112.