abstract |
The invention discloses a synthesis process of 1-chloro-1'-chloroacetyl cyclopropane, which belongs to the technical field of fine chemical industry. The process uses α-acetyl-γ-butyrolactone and sulfonyl chloride as raw materials to obtain the target product through four steps of chlorination, ring opening, ring closure and re-chlorination. The synthesis method uses cheap industrial chemicals as raw materials and reaction reagents, adopts a single solvent system, realizes smooth process connection, improves reaction yield, simplifies process operation, reduces raw material cost and reduces production cost. |