http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104288102-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b93c2aafeb1bcb1019daee345cc8f141 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-127 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-704 |
| filingDate | 2014-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1089d63eeb01aebea1c4580a02fbd569 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d1f7eab5cafb447ef24f3482434346bd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_70caa640ad7061a5fa5b2d12c8595a91 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b5013f76c1520d289dd6b295e59219e3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_30681b21a66efef057967523e2e8cfda http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_66753370ee7b8b8bff5ed35051a045fe http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_87ed1e2fabc34eb79177dbbe7eacd48f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8a3b0e8b86dc75819f775c51dadcb5d6 |
| publicationDate | 2015-01-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104288102-A |
| titleOfInvention | Method for preparing antibody target modified Alzheimer disease targeted drug delivery compound and application of antibody target modified Alzheimer disease targeted drug delivery compound |
| abstract | The invention relates to an antibody target modified Alzheimer disease targeted drug delivery compound. According to the compound, hydrogenated soybean lecithin and cholesterol form a phospholipid bilayer structure, distearoyl phosphoethanolamine-polyethylene glycol is interpenetrated in the phospholipid bilayer, water-soluble drugs are coated in lipidosome, and an antibody is modified on the surface of the lipidosome. The invention further relates to a preparation method and application of the targeted drug delivery compound. The targeted drug delivery compound has the advantages that a targeted nano-drug delivery system has excellent biocompatibility; hydrophilic drugs are coated in the bilayer lipidosome by means of physical effect; compared with a free drug, the targeted drug delivery compound has the beneficial effects of remarkably improving the drug target, prolonging the circulating time of the drug in a body and improving the biological utilization of the drug; and a non-invasive administration mode is provided to treatment of Alzheimer disease. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-110638760-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107693800-A |
| priorityDate | 2014-10-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 106.