abstract |
The present invention relates to novel compounds of formula I, wherein A 1 , A 2 , A 3 , A 4 , A 5 , A 6 , R 2 , R 4 , R 5 , R 6 , R 7 , R 8 and subscript m and n each has the meaning stated in the text. Compounds of formula I and pharmaceutical compositions thereof are useful in the treatment of diseases and conditions in which undesired or excessive activation of NF-kB signaling is observed. |