http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104278035-B
Outgoing Links
Predicate | Object |
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P7-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-115 |
filingDate | 2013-07-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2017-04-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2017-04-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-104278035-B |
titleOfInvention | A kind of fibrin ferment aptamer of different thymidine modification and its preparation method and application |
abstract | The invention discloses a kind of fibrin ferment aptamer of different thymidine modification and its preparation method and application, belongs to biomedicine field.The present invention is by the incorporation Formula I in the fibrin ferment aptamer of synthesis and/or the different thymidine shown in II, so as to obtain a kind of fibrin ferment aptamer of different thymidine modification, experiment proves the human body blood coagulation enzymatic nucleic acid aptamers through the method modification, preferably can recognize with fibrin ferment, adhesion is higher, and with higher anticoagulant effect, therefore, it is hopeful for the fibrin ferment aptamer of this different thymidine modification to be prepared into a kind of efficient, high selectivity, the anticoagulation medicine of low toxicity side effect. |
priorityDate | 2013-07-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 84.