http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104262245-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-75 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-76 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-76 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-75 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-496 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-02 |
| filingDate | 2014-08-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104262245-B |
| titleOfInvention | A kind of 6-phenylpyridine-2-amine Bcr-Abl inhibitor and its preparation method and application |
| abstract | The invention discloses a kind of 6-phenylpyridine-2-amine Bcr-Abl inhibitor and its preparation method and application, the structural formula of this inhibitor is Wherein R 1 For acetyl groups, Mesylation group or pivaloyl group, R 2 For monosubstituted base or disubstituted, substituent group is alkyl, halogen.ABL1 kinases is had certain inhibitory action by this inhibitor series in vitro, and can suppress the propagation of tumor cell K562, can be used for the preparation of antitumor drug, especially CML (chronic myelocytic leukemia) medicine.The preparation method of 6-phenylpyridine-2-amine Bcr-Abl inhibitor provided by the invention, has raw material and is easy to get, and reaction condition is gentle, and course of reaction is simple to operate, the advantage that agents useful for same is cheap. |
| priorityDate | 2014-08-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 89.