http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104258395-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 |
| filingDate | 2014-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-01-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2017-01-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104258395-B |
| titleOfInvention | Functions and applications of nucleotide synthetase CAD in treatment of atherosclerosis |
| abstract | The invention discloses functions and applications of nucleotide synthetase CAD in treatment of atherosclerosis, belonging to the fields of functions and applications of genes. ApoE-/- mice and CAD-/-ApoE-/- mice are taken as experimental subjects, an atherosclerosis model is obtained through high fat diet induction, the result proves that compared with the ApoE-/- mice, the plaque area of the aorta is obviously reduced due to the CAD gene defects, the stability of sinus plaques of the aorta is enhanced, and the inflammatory response is obviously alleviated. The functions of the CAD in atherosclerosis mainly refer to the effects of promoting aorta plaque formation, particularly the effect of promoting the atherosclerosis. Aiming at the functions of the CAD, the CAD can serve as a drug target to be used for screening medicines for preventing, relieving and/or treating the atherosclerosis, and inhibitors of the CAD can be used for preparing medicines for preventing, relieving and/or treating the atherosclerosis. |
| priorityDate | 2014-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1227.