http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104250638-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-93 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-01 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P31-14 |
| filingDate | 2014-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-01-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2017-01-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104250638-B |
| titleOfInvention | Porcine reproductive and respiratory syndrome virus attenuated strain, vaccine composition and preparation method and application thereof |
| abstract | The invention provides a porcine reproductive and respiratory syndrome virus attenuated strain. The porcine reproductive and respiratory syndrome virus is a novel recombinant chimeric virus obtained by respectively substituting a Nsp9 gene and a Nsp10 gene of a highly pathogenic porcine reproductive and respiratory syndrome virus strain with a Nsp9 gene and a Nsp10 gene of a classic porcine reproductive and respiratory syndrome virus attenuated strain. The porcine reproductive and respiratory syndrome virus attenuated strain can further contain a GP5 gene of the highly pathogenic porcine reproductive and respiratory syndrome virus attenuated strain. The invention also discloses a vaccine composition containing the attenuated strain and application thereof to preparation of drugs for preventing and / or treating porcine reproductive and respiratory syndrome. The attenuated strain overcomes the security problems of the artificial passage attenuated vaccine; the vaccine composition prepared from the attenuated strain not only can be used for the prevention of common porcine reproductive and respiratory syndrome but also can prevent highly pathogenic porcine reproductive and respiratory syndrome. |
| priorityDate | 2014-04-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 524.