http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104232777-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6869 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16B30-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M1-34 |
| filingDate | 2014-09-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104232777-B |
| titleOfInvention | Determine the method and device of fetal nucleic acid content and chromosomal aneuploidy simultaneously |
| abstract | The invention provides the method for fetal nucleic acid content in anemia of pregnant woman's body fluid sample that determines, determine fetal nucleic acid content and the method for fetal chromosomal variation information, the non-diagnostic method detecting fetal nucleic acid variation in anemia of pregnant woman's body fluid sample and respective device in anemia of pregnant woman's body fluid sample simultaneously, in described determination anemia of pregnant woman's body fluid sample, the method for fetal nucleic acid content includes: obtain anemia of pregnant woman's body fluid sample；Extracting a DNA and the 2nd DNA, a DNA from sample is parent and foetal DNA mixture, and the 2nd DNA is maternal gene group DNA；To obtain the first reading section and second, an at least one of DNA and at least one of second DNA sequencing are read section, and first reads section and second reads to comprise multiple pleomorphism site in section；By first read section and second read section respectively with reference sequences comparison, based on obtain comparison result, filter out and pleomorphism site only have a kind of genotype at the 2nd DNA and has the pleomorphism site of two kinds of genotype at a DNA；The first reading section in foundation comparison result is supported the reading hop count mesh of the pleomorphism site filtered out, determines the fetal nucleic acid content in sample. |
| priorityDate | 2014-09-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 64.