http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104231091-B
Outgoing Links
Predicate | Object |
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08B13-00 |
filingDate | 2014-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2016-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2016-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-104231091-B |
titleOfInvention | The preparation method of hydroxypropylmethyl cellulose phthalate |
abstract | The invention belongs to excipient substance field, the preparation method being specifically related to a kind of hydroxypropylmethyl cellulose phthalate。The technical problem to be solved is to provide a kind of hydroxypropylmethyl cellulose phthalate preparation method that can improve phthalyl content。The technical solution adopted in the present invention is for promoting reaction temperature to 85 DEG C~100 DEG C, and maintaining pressure in reaction vessel is 0.3MPa~0.9MPa, reacts 3.5h~6h。The inventive method has reached to increase the purpose of positive reaction by adjustment reaction temperature and reaction pressure, by 21%, phthalyl content in product can be promoted to 25%。And the inventive method synthesis technique is simple, reaction condition is easily-controllable, is suitable for being amplified producing。 |
priorityDate | 2014-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 29.