http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104231013-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7034 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H15-203 |
| filingDate | 2014-08-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-06-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104231013-B |
| titleOfInvention | A kind of gastrodine Glehnilae and preparation method thereof and application |
| abstract | The present invention relates to gastrodine Glehnilae and preparation method thereof and application, effectively solve to combine gastrodine ferulic acid to make gastrodine Glehnilae, and preparation improves and treatment neurasthenia, the medication problem of neurasthenia syndrome and angioneurotic headache, method is, anhydrous glucose acetic anhydride is carried out acetylation, hemiacetal hydroxyl bromo again, then with hydroxy benzaldehyde condensation, hydro-reduction, obtain acegastrodine, the protection of ferulic acid acetylating hydroxyl groups is obtained 3-(4 '-acetyl group-3 '-methoxyphenyl)-2-acrylic acid, prepare Acetylferuloyl Chloride again；Acegastrodine is dissolved in dry solvent, adds nucleophilic acylation catalyst and acid binding agent；Acetylferuloyl Chloride is dissolved in dry solvent, two solution mixing, obtain ester type compound, then deacetylation in the basic conditions, obtain gastrodine Glehnilae；The gastrodine Glehnilae of the present invention has calmness, hypnosis, improves effect of brain blood circulation. |
| priorityDate | 2014-08-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 127.