http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104230811-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b1f70cad3d55b29778811ca826c7ef2c |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D231-54 |
| filingDate | 2014-07-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_52a6f661b28d1da862817da4b8455536 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7df711a450e613991e91c3363dbd8b61 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_796b5fec64cf2e3684137e8374da5cc3 |
| publicationDate | 2014-12-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104230811-A |
| titleOfInvention | A kind of pyrazole pyridine compound and preparation method thereof |
| abstract | The present invention relates to a kind of pyrazolidine compound and preparation method thereof, and this compound is 3-bromo-7-hydroxyl-pyrazole pyridine, and preparation method is as follows: (1) compound 12-chloro-4-methyl-3-amino Pyridine is the starting material, and compound 2 is formed through substitution reaction; (2) compound 2 is ring-closed to form compound 3 pyrazole pyridine; (3) compound 3 is brominated on N-bromosuccinimide to obtain compound 4; (4) using Pyridine hydrochloride makes the methoxy group of compound 4 form phenolic hydroxyl group to obtain compound 5a; (5) compound 5a is protected by acetyl group to obtain compound 6a; (6) compound 6 is deacetylated to obtain the final product compound 7; the obtained final product is in It has broad application prospects in the prevention and treatment of cancer. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105213391-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-105213391-B |
| priorityDate | 2014-07-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 22.