http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104230808-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D223-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-55 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D223-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-55 |
filingDate | 2014-08-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2016-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2016-05-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-104230808-B |
titleOfInvention | Amorphous ivabradine hydrochloride and preparation method thereof and application |
abstract | The invention belongs to pharmaceutical chemistry field, be specifically related to a kind of amorphous ivabradine hydrochloride and preparation method thereof and application. The preparation method of amorphous ivabradine hydrochloride of the present invention, comprise the step of preparing the hydrochloric acid Ivabradine aqueous solution by soluble in water hydrochloric acid Ivabradine, after filtration, get filtrate and under vacuum condition, carry out freeze drying processing, obtain required amorphous ivabradine hydrochloride. This preparation method is reproducible, process stabilizing, be suitable for suitability for industrialized production, and the crystal formation of preparation is to be easy to control as single amorphous ivabradine hydrochloride. |
priorityDate | 2014-08-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 22.