http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104230770-B
Outgoing Links
Predicate | Object |
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classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C317-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C317-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C315-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-277 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-08 |
filingDate | 2013-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2017-11-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2017-11-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-104230770-B |
titleOfInvention | The application of styryl sulfone compound, its preparation method as well as neuroprotective agent |
abstract | The application is related to the CAPE (CAPE) with neuroprotective activity extracted from natural propolis for primer; according to bioisosterism and hydrogen bond action scheduling theory; design the recruit that a kind of sulfone group replaces ester group; its structure is shown in formula I, and the definition of each group is as is described in the claims in formula.Also relate to the evaluation of Compound ira vitro oxidation resistance, the neuroprotective activity evaluation of cellular level and pass through blood-brain barrier merit rating.Activity evaluation shows that the noval chemical compound neuroprotective activity synthesized strengthens and is more easy to by blood-brain barrier, so as to turn into a kind of neuroprotective agent of novel therapeutic nerve degenerative diseases. |
priorityDate | 2013-06-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 255.