http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104225627-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 |
| filingDate | 2014-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-09-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-09-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104225627-B |
| titleOfInvention | The leukocytic immunity globulin sample receptor subfamily B member 4 function and application in treatment atherosclerosis |
| abstract | The invention discloses a kind of leukocytic immunity globulin sample receptor subfamily B member 4(LILRB4) function and application in treatment atherosclerosis, belong to function and the application of gene.The present invention is with ApoE ‑/‑ Mice and LILRB4 ‑/‑ ApoE ‑/‑ Mice is experimental subject, obtains Atherosclerosis Model by high fat diet induction, and result shows and ApoE ‑/‑ Mice contrasts, and LILRB4 genetic flaw significantly increases the plaque area of aorta, reduces the stability of aortic sinus speckle, is significantly degrading inflammatory reaction.This shows LILRB4 function in atherosclerosis, is mainly reflected in LILRB4 and has the effect that suppression Aortic Plaque is formed, and particularly LILRB4 can suppress atherosclerotic effect.For the above-mentioned functions of LILRB4, LILRB4 can be used for preparation prevention, alleviates and/or treat atherosclerotic medicine. |
| priorityDate | 2014-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 119.