http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104225618-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N7-01 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-867 |
| filingDate | 2013-06-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2017-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2017-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104225618-B |
| titleOfInvention | Application of human NLK gene and EGFR gene in curing tumors and related drugs |
| abstract | The invention relates to the field of biotechnology and specifically discloses a separate human NLK gene and an application of the human NLK gene and a human EGFR gene used as synergistic drug targets in the preparation or screening of drugs for curing tumors. The invention also further constructs an NLK gene small interfering RNA, an NLK gene interfering lentiviral vector and an NLK gene interfering lentivirus and discloses an application of the NLK gene small interfering RNA, the NLK gene interfering lentiviral vector and the NLK gene interfering lentivirus in cooperation with the EGFR gene in curing tumors. The siRNA or the lentiviral vector containing siRNA sequence or the lentivirus containing siRNA sequence provided by the invention can inhibit expression of the human NLK gene and/or the human NLK gene specifically, especially the lentivirus. The NLK gene interfering lentivirus can inhibit tumor cell growth and promote tumor cell apoptosis separately or in cooperation with the EGFR gene interfering lentivirus, and is of great significance in curing tumors. |
| priorityDate | 2013-06-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 113.