http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104225614-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08J3-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08J3-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-54 |
| filingDate | 2014-09-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104225614-B |
| titleOfInvention | With chitosan grafted polylactic acid complex microsphere carrying hydrophobe biomolecule and preparation method thereof |
| abstract | The invention discloses a kind of with chitosan grafted polylactic acid complex microsphere carrying hydrophobe biomolecule and preparation method thereof, belong to bio-medical material, functionalized macromolecular microsphere and drug controlled release technical field.This complex microsphere is collectively constituted by chitosan grafted polylactic acid and hydrophilic biomolecule, hydrophobic biomolecules.The preparation of described complex microsphere is first to be dissolved in by hydrophobic biomolecules in chitosan grafted polylactic acid solution, form hud typed micellar solution, it is subsequently adding hydrophilic biomolecule, under the effect of surfactant, the micellar solution obtained is added drop-wise in oil phase, form water-in-oil type mixed emulsion, and then addition cross-linking agent, make micellar solution cross-link balling-up further, formed with the chitosan grafted polylactic acid complex microsphere carrying hydrophobe biomolecule.What the present invention obtained is the complex microsphere of a kind of novelty, it is achieved that the subregion distribution of hydrophobe biomolecule, gets a good chance of being used widely at drug controlled release and Repair of tissue defect field. |
| priorityDate | 2014-09-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 62.