http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104224728-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4439 |
| filingDate | 2014-08-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104224728-B |
| titleOfInvention | A kind of Esomeprazole enteric pellet and preparation method thereof |
| abstract | The invention discloses enteric coated pellets formulation of a kind of esomeprazole and preparation method thereof, it is prepared by pastille micropill bag contagion gown and enteric coating；This pastille micropill includes celphere, esomeprazole active component, crystal stabilization, basifier；Described esomeprazole active component is the crystalline hydrate of esomeprazole strontium salt or magnesium salt；Described crystal stabilization is polyoxyethylene PEO and the mixture of the mixture of hypromellose or polyoxyethylene PEO with polyvinylpyrrolidone；The weight proportion of described esomeprazole active component, crystal stabilization and basifier is 20:4 10:10 20.Add a certain proportion of crystal stabilization in the specific solvent of place of the present invention, basifier makes esomeprazole strontium or magnesium salt obtains high optics, crystal form purity pharmaceutical preparation.In said preparation clinical practice safely, effectively, solve existing for current like product prominent release risk, take medicine after the bigger defect of side effect, product has higher quality stability. |
| priorityDate | 2014-08-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 80.