http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104211753-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cb351a5a4e03ee3773bd0df5dbae9ac3 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-46 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-09 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-71 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K1-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K41-00 |
| filingDate | 2014-09-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e368774ec0a10807f6ed97a027842cb6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7d236f6a1b36e6a20f4eb224211b51c6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a3bd18b265b53ef18d41963c8cfed94d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ee04459cc34b43b858d56c210fb29f1c |
| publicationDate | 2014-12-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104211753-A |
| titleOfInvention | Bacterial nano magnetic corpuscle-glycosphingolipid compound and preparation method and application of compound |
| abstract | The invention discloses a bacterial nano magnetic corpuscle-glycosphingolipid compound and a preparation method and an application of the compound, and belongs to the fields of separation and medicines. The BMPs-glycosphingolipid compound disclosed by the invention is prepared by the following steps: firstly, removing surface proteins of BMPs by using a surfactant; suspending the BMPs into a glycosphingolipid solution; and carrying out ultrasonic or room-temperature reaction, and incubating to couple the BMPs to the glycosphingolipid, thereby obtaining the bacterial nano magnetic corpuscle-glycosphingolipid compound. Irrelevant protein is effectively prevented from being introduced by removal of the surface proteins, and the protein acting with the glycosphingolipid can be obtained. The compound disclosed by the invention can be used for promoting utilization of the glycosphingolipid by cells, meanwhile, magnetic particles in the compound can play a targeting effect, and the compound is guided to be gathered towards the focus part, so that the drug targeting property is relatively high. After the compound is introduced into the tumor region, magnetic targeting thermal therapy can also be introduced, thereby further treating the focus. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107708735-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104624176-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104624176-A |
| priorityDate | 2014-09-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 129.