http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104211676-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D313-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-14 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D313-12 |
filingDate | 2009-07-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2017-07-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2017-07-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-104211676-B |
titleOfInvention | The method for obtaining olopatadine and intermediate |
abstract | Olopatadine can be obtained by the method including the logical formula (II) compound of hydrolysis, and wherein Y is OR 1 , wherein R 1 It is C 1‑ C 7 Alkyl, C 3‑ C 7 Cycloalkyl, aryl, aralkyl or heterocycle;Or Y is NR 2 R 3 , wherein R 2 And R 3 It is independently of one another C 1‑ C 7 Alkyl, aryl, aralkyl, or R 2 And R 3 The nitrogen-atoms being bonded together with them forms 3 yuan to 7 circle heterocycles, in the reaction medium comprising organic solvent, in the presence of base, above-mentioned logical formula (II) compound is by including 6, [the corresponding ester or acid amides of the acetic acid of b, e] Evil English in heptan 2 react and obtain the oxo dibenzo of 11 dihydro 11 with appropriate Wittig reagent. |
priorityDate | 2008-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 108.