http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104211605-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C213-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C213-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C65-03 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C51-43 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C51-41 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C215-44 |
| filingDate | 2014-08-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-04-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104211605-B |
| titleOfInvention | A kind of Transbroncho and m-Salicylic acid eutectic and preparation method thereof |
| abstract | The invention belongs to technical field of pharmaceutical co-crystal, be specifically related to a kind of novel Transbroncho pharmaceutical co-crystals and preparation method thereof.The Transbroncho pharmaceutical co-crystals spacer that the present invention prepares is oblique system, and a Transbroncho molecule passes through, together with hydrogen bonded, to form the elementary cell of Transbroncho pharmaceutical co-crystals with a m-Salicylic acid.The solvent that eutectic preparation process is selected is the mixed system of first alcohol and water, and employing method is solvent room temperature volatilization method, because the boiling point of selected solvent is relatively low, therefore in the process of solvent evaporates, has crystal separate out.Pharmaceutical co-crystals prepared by the present invention, outside the speciality such as the eliminating of the inner thick secretions of the promotion respiratory tract maintaining Transbroncho and the delay of minimizing mucus, is significantly improved in its stability. |
| priorityDate | 2014-08-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 28.