http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104193749-B
Outgoing Links
Predicate | Object |
---|---|
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-10 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-10 |
filingDate | 2014-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate | 2017-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationDate | 2017-02-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | CN-104193749-B |
titleOfInvention | Double-spiro compound containing isatin mother nucleus with antineoplastic activity and synthesis method thereof |
abstract | The invention discloses a compound shown in a structural general formula (I) in the Specification and a synthesis method thereof. The double-spiro compound containing the isatin mother nucleus uses pulegone, isatin and derivatives thereof, and sarcosine as raw materials, and the synthesis process uses a one-pot method, so that complicated multi-step operations are avoided, the operation is simple and convenient, the reaction conditions are mild, and the yield is better. The bioactivity tests show that the double-spiro compound containing the isatin mother nucleus has better antineoplastic activity. |
priorityDate | 2014-09-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 626.