http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104177632-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08J3-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08K5-17 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08J3-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D317-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08J3-09 |
| filingDate | 2014-08-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104177632-B |
| titleOfInvention | A kind of by the core crosslinking micelle prepared containing two pentacyclic cross-linking agent of ortho esters and synthetic method thereof and application |
| abstract | The invention discloses a kind of core prepared by two pentacyclic cross-linking agent of ortho esters crosslinking micelle and synthetic method thereof and application, belong to polymer support and slow controlled-release material technical field.The structure of the described core crosslinking micelle prepared by two pentacyclic cross-linking agent of ortho esters is as shown in chemistry formula I.Utilizing amphipathic nature block polymer PEG-b-PNSM to be self-assembly of micelle in aqueous, the crosslinking micelle adding cross-linking agent formation can carry the medicine (such as antitumor paclitaxel) being insoluble in water in vivo.The core crosslinking micelle of the present invention has good sensitivity to acid, biocompatibility and biodegradability, has a good application prospect in targeted therapy field. In formula, X represents numerical value 20-200. |
| priorityDate | 2014-08-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 44.