http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104173402-B

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classificationIPCAdditional http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K133-00
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
filingDate 2014-08-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2018-01-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2018-01-02-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber CN-104173402-B
titleOfInvention The preparation method and its anticancer purpose of general flavone in a kind of Inula britannica chinensis medicinal material
abstract The preparation method of general flavone in a kind of Inula britannica chinensis medicinal material, including following processes:(1)Take Inula britannica chinensis appropriate, add the ethanol of 5 30 times of amounts 30 95%, refluxing extraction 13 times, 1 5h, filtering, filtrate merging are standby as extract solution every time;(2)By step(1)The Inula britannica chinensis extract solution produced, it is 0.05 0.5g/ml that heating, which is concentrated into extract concentration, and regulation pH value is 17, as sample solution;(3)Sample solution purifies:By sample solution made from step 2, upper HPD300 macroreticular resins, crude drug and resin demand ratio be 0.1 1.0g/ml, after the removal of impurities of 3 10BV water, then 10 95% ethanol elutions with 3 10BV, once general flavone content >=70% after purification.Purity increase of the present invention, taking dose can be reduced, reduce adverse reaction, while as raw material there is the PTS of extensive Clinical practice value and business development value and industrial production to provide theoretical and experimental basis using inula japonica total flavone enrichment substance to develop.
priorityDate 2014-08-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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