http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104173378-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6f98752405f8b50c10955ba08c2b8d9b |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K33-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2014-09-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_771b830a71c2eb483ded5bf1660202af http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4d128892175b5c615ef72f364eb2311f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_53fb8989b720e5945161b66686a9a673 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_06941250fa33542d8b57e8bdd4167c6e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e48bd23e6c9a0f6760877c60acad5eaa http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_18fedb02941ad83bec27f81547d7394d |
| publicationDate | 2014-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104173378-A |
| titleOfInvention | Preparation method of targeted controlled release arsenical medicine |
| abstract | The invention discloses a preparation method of a targeted controlled release arsenical medicine. The preparation process comprises three steps: preparation of an arsenical medicine-loaded magnetic Fe3O4 core, coating of the magnetic arsenical medicine by nanosilicon dioxide and biocompatibility of the arsenical medicine. According to the preparation method disclosed by the invention, the arsenical medicine and porous magnetic Fe3O4 are coprecipitated and the arsenical medicine is adsorbed on the surface of the magnetic Fe3O4, so that the release speed is delayed. The arsenical medicine is coated by using porous nanosilicon dioxide so as to realize targeted long-acting release and controlled release of the arsenical medicine. Surface treatment is carried out on the arsenical medicine by using a polyvinylpyrrolidone macromolecular sol, so that the biocompatibility is improved. The preparation method disclosed by the invention can be used for solving the problem that an existing controlled release arsenical medicine preparation process is complex and unstable in release speed, and can be used for realizing targeted delivery, reducing the side effects of the medicine and improving the curative effect. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104825488-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104825488-B |
| priorityDate | 2014-09-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 46.