| abstract |
The invention provides a sustained release tablet containing felodipine and metoprolol salt and a preparation method of the sustained-release tablet containing the felodipine and the metoprolol salt. The sustained-release tablet is prepared from metoprolol salt sustained-release pill, a felodipine sustained-release pill, tablet filling granules and a film coating layer, and is characterized in that the dissolution curve of the metoprolol salt sustained-release pill and the dissolution curve of the felodipine sustained-release pill do not have remarkable changes before and after tabletting. The sustained-release tablet has the advantage that the dissolution speed of active components is still kept to be constant even the tablet is broken into pieces, and can be durably slowly released in 24 hours. |