| Predicate |
Object |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D273-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D413-14 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D491-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D513-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D498-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D498-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D498-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D491-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4353
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D491-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D498-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D498-18
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D498-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D513-18 |
| filingDate |
2013-02-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
2016-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate |
2016-06-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
CN-104169286-B |
| titleOfInvention |
Macrocyclic derivatives for the treatment of proliferative diseases |
| abstract |
The present invention relates to compounds of formula (Φ) (which is further defined herein) and relates to pharmaceutically acceptable salts thereof, pharmaceutical compositions containing the compounds and salts and uses thereof. The compounds and salts of the present invention inhibit anaplastic lymphoma enzyme (ALK) and/or EML4-ALK and are useful for treating or ameliorating abnormal cell proliferative disorders such as cancer. |
| priorityDate |
2012-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |