http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104163823-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D519-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4745 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D519-00 |
| filingDate | 2014-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-03-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104163823-B |
| titleOfInvention | A kind of camptothecine and Artesunate conjugate and preparation method thereof and application |
| abstract | The invention discloses the camptothecine shown in a kind of formula (I) and Artesunate conjugate, its preparation method is: be dissolved in organic solvent by Artesunate shown in camptothecine formula (II) Suo Shi and formula (III), under the effect of 1-ethyl-(3-dimethylaminopropyl) carbodiimide hydrochloride and DMAP, in 15 ~ 50 DEG C of stirring reactions, TLC tracking monitor no longer carries out to reaction, reaction solution aftertreatment, obtains the camptothecine shown in formula (I) and Artesunate conjugate; Camptothecine of the present invention and Artesunate conjugate can be used for preparing antitumor drug; |
| priorityDate | 2014-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 68.