http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104163814-B
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 |
| filingDate | 2014-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 2016-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2016-08-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104163814-B |
| titleOfInvention | A kind of high-purity 5-methoxyl group-2-((S)-((4-methoxyl group-3,5-dimethyl-2-pyridine radicals) methyl) sulfinyl)-1H-benzimidazole sodium preparation method |
| abstract | The invention discloses the preparation method of a kind of high-purity 5 methoxyl group 2 ((S) ((4 methoxyl group 3,5 dimethyl 2 pyridine radicals) methyl) sulfinyl) 1H benzimidazole sodium.It is mainly used in the refined of 5 methoxyl group 2 ((S) ((4 methoxyl group 3,5 dimethyl 2 pyridine radicals) methyl) sulfinyl) the 1H benzimidazole sodium crude products that prochiral compound synthesizes through asymmetric oxidation reaction.Described preparation method includes: by 5 methoxyl group 2 ((S) ((4 methoxyl groups 3, 5 dimethyl 2 pyridine radicals) methyl) sulfinyl) crude product of 1H benzimidazole sodium, first add rudimentary Organic Alcohol at normal temperatures, stir the most under cryogenic to after the most molten, start to drip acetonitrile, drip complete intensification to stir to crystal precipitation, filter, drying obtains 5 methoxyl group 2 ((S) ((4 methoxyl groups 3, 5 dimethyl 2 pyridine radicals) methyl) sulfinyl) 1H benzimidazole sodium highly finished product, the method technique is simple, yield is high, it is applicable to industrialized great production, and the completed optical purity finally prepared reaches more than 99.9%, content is up to more than 99.6%. |
| priorityDate | 2014-05-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 37.