http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-104152526-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_be3342a254721cecb991f53d44486c84 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P13-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C209-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C211-27 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P41-00 |
| filingDate | 2014-08-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6dadd0e17106ed9d6082244ebec9a41f |
| publicationDate | 2014-11-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | CN-104152526-A |
| titleOfInvention | A method for splitting and preparing optically pure R-1-phenylethylamine |
| abstract | The invention relates to a method for preparing R-1-phenethylamine by dynamic kinetic resolution. Using 1-phenylethylamine as raw material, Novozym435 as resolution catalyst, D-(-)-O-acetylmandelic acid as acyl donor, KT-02 (nickel type catalyst) as racemization catalyst, in an autoclave Introduce hydrogen to react, and 1-phenylethylamine is completely converted to obtain (R)-(1-phenylethyl)acetamide (ee value 99%); after purification of the amide, acidolysis is carried out to obtain R-1-phenylethylamine salt , the salt is then subjected to operations such as alkalization, extraction, drying, and concentration to obtain R-1-phenylethylamine, and the product yield and ee value of the whole step can reach more than 90%. The invention has the characteristics of cheap and easy-to-obtain racemization catalyst, complete utilization of raw materials, good product yield, high purity and the like. In the production and preparation of R-1-phenylethylamine, it has great guiding and application value. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-109651158-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-115583867-A |
| priorityDate | 2014-08-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 19.